In 2092, while Lionel and Adrian attempt to return their lives to normality, the plague continues to spread across Europe and the Americas, and reports of a black sun cause panic throughout the world. At first England is thought to be safe, but soon the plague reaches even there. Ryland, recently elected Lord Protector, is unprepared for the plague, and flees northward, later dying alone amidst a stockpile of provisions. Adrian takes command and is largely effective at maintaining order and humanity in England, although the plague rages on summer after summer. Ships arrive in Ireland carrying survivors from America, who lawlessly plunder Ireland and Scotland before invading England. Adrian raises a military force against them, but ultimately is able to resolve the situation peacefully.

Mary Shelley’s The Last Man at Wikipedia